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Coagulopathy Associated With Trauma: A Rapid Review for Prehospital Providers

Summer 2022

Friedman J, Ditzel RM, Fisher AD. 22(2). 110 - 115. (Journal Article)


The coagulopathy associated with trauma is a complex and convoluted process that is still poorly understood. However, there are recognized contributors to acute traumatic coagulopathy (ATC) and trauma induced coagulopathy (TIC) that are universal. They are hypothermia, acidosis, and coagulopathy, also known as the lethal triad. Recently, with new understanding of hypocalcemia's role in trauma mortality, the term lethal diamond has been coined to underscore calcium's importance. Prehospital providers often unknowingly exacerbate ATC and TIC with excessive crystalloid administration and poor hypothermia prevention. This article will serve as an overview of the physiologic and iatrogenic drivers of ATC and TIC, and will discuss how they can be prevented, assessed, and treated.

Keywords: lethal triad; critical care; prehospital; coagulopathy; trauma; resuscitation; lethal diamond

PMID: 35649406

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